Magnus, Carsten, Dr.

In January 2007 I began a PhD with Dr. Roland Regoes. In June 2010 I passed my PhD defense and I am now working as a postdoc with Roland Regoes.
I use mathematical models to address problems emerging from and inspired by virology and immunology. Having a strong probabilistic background, I am especially interested in applying probabilistic methods such as branching processes or mathematical population genetics. Here are two examples of what I am working on:

How many antibodies are needed to neutralize viruses?
This question can be broken down to the study of the numerical requirements for viral entry and the number of antibodies rendering one viral spike non-functional. As these questions cannot be answered by experiments directly, mathematical models are required.

Which immune system characteristics do optimally protect against repeated pathogen encounters?
Our immune system has evolved as a response to a diverse pathogen environment. Has the pathogen environment also influenced the evolution of different immune memory characteristics? Such characteristics are for example the number of memory cells, the immune system can store in total or the patterns of storing memory cells after a survived infection. Simulating the exposure of individuals to different pathogens allows tracking the evolution of immune memory characteristics in silico.

CV

Publications

ECMTB2011